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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FADD
All Species:
22.42
Human Site:
S122
Identified Species:
54.81
UniProt:
Q13158
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13158
NP_003815.1
208
23279
S122
L
A
R
Q
L
K
V
S
D
T
K
I
D
S
I
Chimpanzee
Pan troglodytes
XP_508611
208
23330
S122
L
A
R
Q
L
K
V
S
D
T
K
I
D
S
I
Rhesus Macaque
Macaca mulatta
XP_001100468
207
23078
S122
L
A
R
Q
L
K
V
S
D
A
K
I
D
S
I
Dog
Lupus familis
XP_854485
175
19520
T79
L
A
R
Y
L
K
V
T
D
A
K
I
D
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61160
205
22942
S122
L
A
R
E
L
K
V
S
E
A
K
M
D
G
I
Rat
Rattus norvegicus
NP_690920
208
23106
S122
L
A
R
E
L
K
V
S
E
A
K
I
D
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507113
190
22233
D94
S
A
T
E
D
L
L
D
P
R
E
R
E
R
L
Chicken
Gallus gallus
XP_421073
195
22801
Q103
D
M
K
E
R
R
L
Q
K
V
V
I
E
V
I
Frog
Xenopus laevis
NP_001089017
188
21457
G92
I
G
D
S
L
A
P
G
T
Q
E
R
D
P
L
Zebra Danio
Brachydanio rerio
XP_001923893
192
22093
T109
R
E
R
I
N
T
A
T
E
V
V
V
E
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
93.7
48
N.A.
67.7
68.2
N.A.
44.2
43.2
37.5
35
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
95.6
60.5
N.A.
84.6
82.2
N.A.
64.4
63.4
58.1
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
73.3
N.A.
6.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
40
46.6
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
0
0
10
10
0
0
40
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
0
0
10
40
0
0
0
70
0
0
% D
% Glu:
0
10
0
40
0
0
0
0
30
0
20
0
30
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
10
0
0
0
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
0
60
0
0
70
% I
% Lys:
0
0
10
0
0
60
0
0
10
0
60
0
0
0
0
% K
% Leu:
60
0
0
0
70
10
20
0
0
0
0
0
0
0
30
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
0
0
10
0
% P
% Gln:
0
0
0
30
0
0
0
10
0
10
0
0
0
10
0
% Q
% Arg:
10
0
70
0
10
10
0
0
0
10
0
20
0
10
0
% R
% Ser:
10
0
0
10
0
0
0
50
0
0
0
0
0
30
0
% S
% Thr:
0
0
10
0
0
10
0
20
10
20
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
60
0
0
20
20
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _